Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and Remodeling

BACKGROUND: Frequent exacerbations of allergic asthma leads to airway remodeling and a decline in pulmonary function, producing morbidity. Cat dander is an aeroallergen associated with asthma risk. OBJECTIVE: We sought to elucidate the mechanism of cat dander-induced inflammation-remodeling. METHODS...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Tian, Bing, Hosoki, Koa, Liu, Zhiqing, Yang, Jun, Zhao, Yingxin, Sun, Hong, Zhou, Jia, Rytting, Erik, Kaphalia, Lata, Calhoun, William J, Sur, Sanjiv, Brasier, Allan R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490683/
https://ncbi.nlm.nih.gov/pubmed/30321559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.09.029
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