PHARMACOPROTEOMICS REVEAL NOVEL PROTECTIVE ACTIVITY OF BROMODOMAIN CONTAINING 4 INHIBITORS ON VASCULAR HOMEOSTASIS IN TLR3-MEDIATED AIRWAY REMODELING

Small molecule inhibitors of the epigenetic regulator bromodomain-containing protein 4 (BRD4) are potential therapeutics for viral and allergen-induced airway remodeling. A limitation of their preclinical advancement is the lack of detailed understanding of mechanisms of action and biomarkers of eff...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Proteomics
Main Authors: Zhao, Yingxin, Bing, Tian, Sun, Hong, Zhang, Jing, Zhang, Yueqing, Ivannikov, Maxim, Motamedi, Massoud, Liu, Zhiqing, Zhou, Jia, Kaphalia, Lata, Calhoun, William J., Maroto, Rosario, Brasier, Allan R
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699176/
https://ncbi.nlm.nih.gov/pubmed/31195152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2019.103415
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados