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Selective affinity enrichment of nitrotyrosine-containing peptides for quantitative analysis in complex samples

Protein tyrosine nitration by oxidative and nitrate stress is important in the pathogenesis of many inflammatory or aging-related diseases. Mass spectrometry analysis of protein nitrotyrosine is very challenging because the non-nitrated peptides suppress the signals of the low-abundance nitrotyrosin...

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Bibliographische Detailangaben
Veröffentlicht in:J Proteome Res
Hauptverfasser: Zhao, Yingxin, Zhang, Yueqing, Sun, Hong, Maroto, Rosario, Brasier, Allan R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656043/
https://ncbi.nlm.nih.gov/pubmed/28714690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00275
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