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A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
BACKGROUND: There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study (GWAS) data across several traits, usually at the summary statistic level. A major practical chal...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6019513/ https://ncbi.nlm.nih.gov/pubmed/29940862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4859-7 |
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