Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes

Blood pressure is a critical determinant of cardiovascular morbidity and mortality. It is affected by environmental factors, but has a strong heritable component. Despite recent large genome-wide association studies, few genetic risk factors for blood pressure have been identified. Epidemiological s...

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Detalhes bibliográficos
Main Authors: Andreassen, Ole A., McEvoy, Linda K., Thompson, Wesley K., Wang, Yunpeng, Reppe, Sjur, Schork, Andrew J., Zuber, Verena, Barrett-Connor, Elizabeth, Gautvik, Kaare, Aukrust, Pål, Karlsen, Tom H., Djurovic, Srdjan, Desikan, Rahul S., Dale, Anders M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984909/
https://ncbi.nlm.nih.gov/pubmed/24396023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02077
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