Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription
In order to explore the defense mechanism by which retrotransposons are repressed, we assessed the ability of methyl-CpG-binding protein 2, MeCP2, to influence LINE-1 (L1) and Alu transcription and, furthermore, L1 retrotransposition. In transient transfection assays, targeting of the transcriptiona...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.4493 |
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