Methyl-CpG-Binding Protein MeCP2 Represses Sp1-Activated Transcription of the Human Leukosialin Gene When the Promoter Is Methylated

Human leukosialin (CD43) is expressed in a cell lineage-specific as well as a differentiation stage-specific fashion. The leukosialin promoter, made up of an Sp1 binding site and a sequence similar to that of an initiator, possesses high transcriptional potential. Previous data have demonstrated tha...

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Bibliographic Details
Main Author: Kudo, Shinichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109134/
https://ncbi.nlm.nih.gov/pubmed/9710633
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