Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription

In order to explore the defense mechanism by which retrotransposons are repressed, we assessed the ability of methyl-CpG-binding protein 2, MeCP2, to influence LINE-1 (L1) and Alu transcription and, furthermore, L1 retrotransposition. In transient transfection assays, targeting of the transcriptiona...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Yu, Fang, Zingler, Nora, Schumann, Gerald, Strätling, Wolf H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.4493
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