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Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription

In order to explore the defense mechanism by which retrotransposons are repressed, we assessed the ability of methyl-CpG-binding protein 2, MeCP2, to influence LINE-1 (L1) and Alu transcription and, furthermore, L1 retrotransposition. In transient transfection assays, targeting of the transcriptiona...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, Fang, Zingler, Nora, Schumann, Gerald, Strätling, Wolf H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC60185/
https://ncbi.nlm.nih.gov/pubmed/11691937
Tagiau: Ychwanegu Tag
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