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Diabetes Drug Discovery: hIAPP(1–37) Polymorphic Amyloid Structures as Novel Therapeutic Targets
Human islet amyloid peptide (hIAPP(1–37)) aggregation is an early step in Diabetes Mellitus. We aimed to evaluate a family of pharmaco-chaperones to act as modulators that provide dynamic interventions and the multi-target capacity (native state, cytotoxic oligomers, protofilaments and fibrils of hI...
שמור ב:
| הוצא לאור ב: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6017868/ https://ncbi.nlm.nih.gov/pubmed/29562662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030686 |
| תגים: |
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