Drug Development in Conformational Diseases: A Novel Family of Chemical Chaperones that Bind and Stabilise Several Polymorphic Amyloid Structures

The increasing prevalence of conformational diseases, including Alzheimer's disease, type 2 Diabetes Mellitus and Cancer, poses a global challenge at many different levels. It has devastating effects on the sufferers as well as a tremendous economic impact on families and the health system. In...

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Veröffentlicht in:PLoS One
Hauptverfasser: Sablón-Carrazana, Marquiza, Fernández, Isaac, Bencomo, Alberto, Lara-Martínez, Reyna, Rivera-Marrero, Suchitil, Domínguez, Guadalupe, Pérez-Perera, Rafaela, Jiménez-García, Luis Felipe, Altamirano-Bustamante, Nelly F., Diaz-Delgado, Massiel, Vedrenne, Fernand, Rivillas-Acevedo, Lina, Pasten-Hidalgo, Karina, Segura-Valdez, María de Lourdes, Islas-Andrade, Sergio, Garrido-Magaña, Eulalia, Perera-Pintado, Alejandro, Prats-Capote, Anaís, Rodríguez-Tanty, Chryslaine, Altamirano-Bustamante, Myriam M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556714/
https://ncbi.nlm.nih.gov/pubmed/26327208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135292
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