Investigation of an (18)F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

Specific radioligands for in vivo visualization and quantification of cyclic nucleotide phosphodiesterase 2A (PDE2A) by positron emission tomography (PET) are increasingly gaining interest in brain research. Herein we describe the synthesis, the (18)F-labelling as well as the biological evaluation o...

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Publicado en:Molecules
Main Authors: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Kranz, Mathias, Scheunemann, Matthias, Egerland, Ute, Höfgen, Norbert, Briel, Detlef, Steinbach, Jörg, Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017663/
https://ncbi.nlm.nih.gov/pubmed/29498659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030556
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