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Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway

This study aimed to investigate the protective effect of curcumin against carbon tetrachloride (CCl(4))-induced acute liver injury in a mouse model, and to explain the underlying mechanism. Curcumin at doses of 50, 100 and 200 mg/kg/day were administered orally once daily for seven days prior to CCl...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Peng, Xinyan, Dai, Chongshan, Liu, Quanwen, Li, Junke, Qiu, Jingru
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017508/
https://ncbi.nlm.nih.gov/pubmed/29351226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010215
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