Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling

Cadmium (Cd) imparts nephrotoxicity via triggering oxidative stress and pathological signal transductions in renal cells. The present study was performed to explore the protective mechanism of carnosic acid (CA), a naturally occurring antioxidant compound, against cadmium chloride (CdCl(2))-provoked...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Das, Sonjit, Dewanjee, Saikat, Dua, Tarun K., Joardar, Swarnalata, Chakraborty, Pratik, Bhowmick, Shovonlal, Saha, Achintya, Bhattacharjee, Simanta, De Feo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891359/
https://ncbi.nlm.nih.gov/pubmed/31752142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224176
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