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Coexpression of Smad7 and UPA attenuates carbon tetrachloride-induced rat liver fibrosis

BACKGROUND: There is a great need for developing novel therapies to treat liver fibrosis. Previous studies showed that both Smad7 and uPA were inhibitors of liver fibrosis. Therefore, we explored the therapeutic effects of combinational gene therapy with Smad7 and uPA on CCl4-induced liver fibrosis....

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Detalhes bibliográficos
Main Authors: Wang, Baocan, Li, Wenxi, Chen, Yingwei, Wang, Yuqin, Sun, Chao, Chen, Yuanwen, Lu, Hanming, Fan, Jiangao, Li, Dingguo
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560566/
https://ncbi.nlm.nih.gov/pubmed/23018346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.883479
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