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S-allyl-cysteine attenuates carbon tetrachloride-induced liver fibrosis in rats by targeting STAT3/SMAD3 pathway

S-allyl-cysteine (SAC) is one of the major compounds in aged garlic extract, and has been proved to be an endogenous donor of hydrogen sulfide (H(2)S), which plays emerging roles in the gastrointestinal tract and liver. In this study, Sprague-Dawley rats were intraperitoneally injected with a mixtur...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Gong, Zhiqiang, Ye, Huisheng, Huo, Yu, Wang, Lei, Huang, Yanhong, Huang, Min, Yuan, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992555/
https://ncbi.nlm.nih.gov/pubmed/29887949
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