N-acetylcysteine protects against liver injure induced by carbon tetrachloride via activation of the Nrf2/HO-1 pathway

Chronic liver injury is an important clinical problem which eventually leads to cirrhosis, hepatocellular carcinoma and end-stage liver failure. It is well known that cell damage induced by reactive oxygen species (ROS) is an important mechanism of hepatocyte injure. N-acetylcysteine (NAC), a precur...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Cai, Zhaobin, Lou, Qi, Wang, Fugen, Li, Er, Sun, Jingjing, Fang, Hongying, Xi, Jianjun, Ju, Liping
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555781/
https://ncbi.nlm.nih.gov/pubmed/26339453
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