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Transdifferentiation of human adult peripheral blood T cells into neurons

Human cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene targeting. Modeling complex, multigenetic traits...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Tanabe, Koji, Ang, Cheen Euong, Chanda, Soham, Olmos, Victor Hipolito, Haag, Daniel, Levinson, Douglas F., Südhof, Thomas C., Wernig, Marius
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016798/
https://ncbi.nlm.nih.gov/pubmed/29866841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720273115
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