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Transdifferentiation of human adult peripheral blood T cells into neurons

Human cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene targeting. Modeling complex, multigenetic traits...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tanabe, Koji, Ang, Cheen Euong, Chanda, Soham, Olmos, Victor Hipolito, Haag, Daniel, Levinson, Douglas F., Südhof, Thomas C., Wernig, Marius
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016798/
https://ncbi.nlm.nih.gov/pubmed/29866841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720273115
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