Transdifferentiation of human adult peripheral blood T cells into neurons

Human cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene targeting. Modeling complex, multigenetic traits...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tanabe, Koji, Ang, Cheen Euong, Chanda, Soham, Olmos, Victor Hipolito, Haag, Daniel, Levinson, Douglas F., Südhof, Thomas C., Wernig, Marius
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016798/
https://ncbi.nlm.nih.gov/pubmed/29866841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720273115
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