Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1

Direct conversion of nonneural cells to functional neurons holds great promise for neurological disease modeling and regenerative medicine. We previously reported rapid reprogramming of mouse embryonic fibroblasts (MEFs) into mature induced neuronal (iN) cells by forced expression of three transcrip...

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Autors principals: Chanda, Soham, Ang, Cheen Euong, Davila, Jonathan, Pak, ChangHui, Mall, Moritz, Lee, Qian Yi, Ahlenius, Henrik, Jung, Seung Woo, Südhof, Thomas C., Wernig, Marius
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176533/
https://ncbi.nlm.nih.gov/pubmed/25254342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.020
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