Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1

Direct conversion of nonneural cells to functional neurons holds great promise for neurological disease modeling and regenerative medicine. We previously reported rapid reprogramming of mouse embryonic fibroblasts (MEFs) into mature induced neuronal (iN) cells by forced expression of three transcrip...

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Hlavní autoři: Chanda, Soham, Ang, Cheen Euong, Davila, Jonathan, Pak, ChangHui, Mall, Moritz, Lee, Qian Yi, Ahlenius, Henrik, Jung, Seung Woo, Südhof, Thomas C., Wernig, Marius
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176533/
https://ncbi.nlm.nih.gov/pubmed/25254342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.05.020
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