Structure–Activity Relationship of (18)F-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer

A series of phosphoramidate-based prostate specific membrane antigen (PSMA) inhibitors of increasing lipophilicity were synthesized (4, 5, and 6), and their fluorine-18 analogs were evaluated for use as positron emission tomography (PET) imaging agents for prostate cancer. To gain insight into their...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Med Chem
المؤلفون الرئيسيون: Dannoon, Shorouk, Ganguly, Tanushree, Cahaya, Hendry, Geruntho, Jonathan J., Galliher, Matthew S., Beyer, Sophia K., Choy, Cindy J., Hopkins, Mark R., Regan, Melanie, Blecha, Joseph E., Skultetyova, Lubica, Drake, Christopher R., Jivan, Salma, Barinka, Cyril, Jones, Ella F., Berkman, Clifford E., VanBrocklin, Henry F.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2016
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016545/
https://ncbi.nlm.nih.gov/pubmed/27228467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01850
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