Structure–Activity Relationship of (18)F-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer

A series of phosphoramidate-based prostate specific membrane antigen (PSMA) inhibitors of increasing lipophilicity were synthesized (4, 5, and 6), and their fluorine-18 analogs were evaluated for use as positron emission tomography (PET) imaging agents for prostate cancer. To gain insight into their...

詳細記述

保存先:
書誌詳細
出版年:J Med Chem
主要な著者: Dannoon, Shorouk, Ganguly, Tanushree, Cahaya, Hendry, Geruntho, Jonathan J., Galliher, Matthew S., Beyer, Sophia K., Choy, Cindy J., Hopkins, Mark R., Regan, Melanie, Blecha, Joseph E., Skultetyova, Lubica, Drake, Christopher R., Jivan, Salma, Barinka, Cyril, Jones, Ella F., Berkman, Clifford E., VanBrocklin, Henry F.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016545/
https://ncbi.nlm.nih.gov/pubmed/27228467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01850
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