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The Molecular Pruning of a Phosphoramidate Peptidomimetic Inhibitor of Prostate-Specific Membrane Antigen
To identify the pharmacophore of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen (PSMA), a small analog library was designed and screened for inhibitory potency against PSMA. The design of the lead inhibitor was based upon N-acyl derivatives of endogenous substrate f...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2065856/ https://ncbi.nlm.nih.gov/pubmed/17869524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.07.028 |
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