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Phosphoramidate-based peptidomimetic inhibitors of membrane type-1 matrix metalloproteinase

Membrane-type I matrix metalloproteinases (MT1-MMP) is an enzyme critical to the remodeling and homeostasis of extracellular matrix, and when over expressed it contributes to metastasis and cancer cell progression. Because of its role and implication as a biomarker that is upregulated in various can...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Mendes, Desiree E., Wong-On-Wing, Annie, Berkman, Clifford E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701619/
https://ncbi.nlm.nih.gov/pubmed/25815671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14756366.2015.1010528
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