A high-affinity [(18)F]-labeled phosphoramidate peptidomimetic PSMA-targeted inhibitor for PET imaging of prostate cancer

INTRODUCTION: In this study, a structurally modified phosphoramidate scaffold, with improved prostate-specific membrane antigen (PSMA) avidity, stability and in vivo characteristics, as a PET imaging agent for prostate cancer (PCa), was prepared and evaluated. METHODS: p-Fluorobenzoyl-aminohexanoate...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Ganguly, Tanushree, Dannoon, Shorouk, Hopkins, Mark R., Murphy, Stephanie, Cahaya, Hendry, Blecha, Joseph E., Jivan, Salma, Drake, Christopher R., Barinka, Cyril, Jones, Ella F., VanBrocklin, Henry F., Berkman, Clifford E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624265/
https://ncbi.nlm.nih.gov/pubmed/26169882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2015.06.003
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