The Molecular Pruning of a Phosphoramidate Peptidomimetic Inhibitor of Prostate-Specific Membrane Antigen

To identify the pharmacophore of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen (PSMA), a small analog library was designed and screened for inhibitory potency against PSMA. The design of the lead inhibitor was based upon N-acyl derivatives of endogenous substrate f...

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Autores principales: Wu, Lisa Y., Anderson, Marc O., Toriyabe, Yoko, Maung, Jack, Campbell, Tammy Y., Tajon, Cheryl, Kazak, Marat, Moser, Jamie, Berkman, Clifford E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065856/
https://ncbi.nlm.nih.gov/pubmed/17869524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.07.028
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