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Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases
Pin1 is a peptidyl-prolyl isomerase that induces the cis-trans conversion of specific Ser/Thr-Pro peptide bonds in phosphorylated proteins, leading to conformational changes through which Pin1 regulates protein stability and activity. Since down-regulation of Pin1 has been described in several neuro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Prion |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016513/ https://ncbi.nlm.nih.gov/pubmed/29676205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2018.1464367 |
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