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Synthetic prions with novel strain-specified properties

Prions are infectious proteins that possess multiple self-propagating structures. The information for strains and structural specific barriers appears to be contained exclusively in the folding of the pathological isoform, PrP(Sc). Many recent studies determined that de novo prion strains could be g...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Moda, Fabio, T. Le, Thanh-Nhat, Aulić, Suzana, Bistaffa, Edoardo, Campagnani, Ilaria, Virgilio, Tommaso, Indaco, Antonio, Palamara, Luisa, Andréoletti, Olivier, Tagliavini, Fabrizio, Legname, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699842/
https://ncbi.nlm.nih.gov/pubmed/26720726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005354
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