Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases

Pin1 is a peptidyl-prolyl isomerase that induces the cis-trans conversion of specific Ser/Thr-Pro peptide bonds in phosphorylated proteins, leading to conformational changes through which Pin1 regulates protein stability and activity. Since down-regulation of Pin1 has been described in several neuro...

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Bibliografische gegevens
Gepubliceerd in:Prion
Hoofdauteurs: Legname, Giuseppe, Virgilio, Tommaso, Bistaffa, Edoardo, De Luca, Chiara Maria Giulia, Catania, Marcella, Zago, Paola, Isopi, Elisa, Campagnani, Ilaria, Tagliavini, Fabrizio, Giaccone, Giorgio, Moda, Fabio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
Onderwerpen:
Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016513/
https://ncbi.nlm.nih.gov/pubmed/29676205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2018.1464367
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