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Human Mutations in SLC2A9 (Glut9) Affect Transport Capacity for Urate
SLC2A9 or Glut9 is a voltage sensitive urate transporter, mainly expressed in the kidneys, the liver, and the intestine. Human Glut9 loss-of-function mutations were identified in familial hypouricemia, and several single nucleotide polymorphisms (SNPs) were associated with lower serum urate, further...
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| Publicado en: | Front Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016318/ https://ncbi.nlm.nih.gov/pubmed/29967582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00476 |
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