SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney

Uric acid (UA) is a metabolite of purine degradation and is involved in gout flairs and kidney stones formation. GLUT9 (SLC2A9) was previously shown to be a urate transporter in vitro. In vivo, humans carrying GLUT9 loss-of-function mutations have familial renal hypouricemia type 2, a condition char...

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Vydáno v:Pflugers Arch
Hlavní autoři: Auberson, Muriel, Stadelmann, Sophie, Stoudmann, Candice, Seuwen, Klaus, Koesters, Robert, Thorens, Bernard, Bonny, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2018
Témata:
Ion Channels, Receptors and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224025/
https://ncbi.nlm.nih.gov/pubmed/30105595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2190-4
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