SLC2A9 Is a High-Capacity Urate Transporter in Humans

BACKGROUND: Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, and cardiovascular disease. Recent genome-wide association scans have found common genetic variants of SLC2A9 to be a...

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Główni autorzy: Caulfield, Mark J, Munroe, Patricia B, O'Neill, Deb, Witkowska, Kate, Charchar, Fadi J, Doblado, Manuel, Evans, Sarah, Eyheramendy, Susana, Onipinla, Abiodun, Howard, Philip, Shaw-Hawkins, Sue, Dobson, Richard J, Wallace, Chris, Newhouse, Stephen J, Brown, Morris, Connell, John M, Dominiczak, Anna, Farrall, Martin, Lathrop, G. Mark, Samani, Nilesh J, Kumari, Meena, Marmot, Michael, Brunner, Eric, Chambers, John, Elliott, Paul, Kooner, Jaspal, Laan, Maris, Org, Elin, Veldre, Gudrun, Viigimaa, Margus, Cappuccio, Francesco P, Ji, Chen, Iacone, Roberto, Strazzullo, Pasquale, Moley, Kelle H, Cheeseman, Chris
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2008
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561076/
https://ncbi.nlm.nih.gov/pubmed/18842065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050197
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