SLC2A9 Is a High-Capacity Urate Transporter in Humans

BACKGROUND: Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, and cardiovascular disease. Recent genome-wide association scans have found common genetic variants of SLC2A9 to be a...

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Détails bibliographiques
Auteurs principaux: Caulfield, Mark J, Munroe, Patricia B, O'Neill, Deb, Witkowska, Kate, Charchar, Fadi J, Doblado, Manuel, Evans, Sarah, Eyheramendy, Susana, Onipinla, Abiodun, Howard, Philip, Shaw-Hawkins, Sue, Dobson, Richard J, Wallace, Chris, Newhouse, Stephen J, Brown, Morris, Connell, John M, Dominiczak, Anna, Farrall, Martin, Lathrop, G. Mark, Samani, Nilesh J, Kumari, Meena, Marmot, Michael, Brunner, Eric, Chambers, John, Elliott, Paul, Kooner, Jaspal, Laan, Maris, Org, Elin, Veldre, Gudrun, Viigimaa, Margus, Cappuccio, Francesco P, Ji, Chen, Iacone, Roberto, Strazzullo, Pasquale, Moley, Kelle H, Cheeseman, Chris
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561076/
https://ncbi.nlm.nih.gov/pubmed/18842065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050197
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