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Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion

RATIONALE: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. Peptidyl arginine deiminase 4 (PAD4) participates i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Circ Res
Hauptverfasser: Franck, Grégory, Mawson, Thomas L., Folco, Eduardo J., Molinaro, Roberto, Ruvkun, Victoria, Engelbertsen, Daniel, Liu, Xin, Tesmenitsky, Yevgenia, Shvartz, Eugenia, Sukhova, Galina K., Michel, Jean-Baptiste, Nicoletti, Antonino, Lichtman, Andrew, Wagner, Denisa, Croce, Kevin J., Libby, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014872/
https://ncbi.nlm.nih.gov/pubmed/29572206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312494
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