Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion

RATIONALE: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. Peptidyl arginine deiminase 4 (PAD4) participates i...

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Publicat a:Circ Res
Autors principals: Franck, Grégory, Mawson, Thomas L., Folco, Eduardo J., Molinaro, Roberto, Ruvkun, Victoria, Engelbertsen, Daniel, Liu, Xin, Tesmenitsky, Yevgenia, Shvartz, Eugenia, Sukhova, Galina K., Michel, Jean-Baptiste, Nicoletti, Antonino, Lichtman, Andrew, Wagner, Denisa, Croce, Kevin J., Libby, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014872/
https://ncbi.nlm.nih.gov/pubmed/29572206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312494
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