Selective inhibition of matrix metalloproteinase 13 (MMP-13) increases collagen content of established mouse atheromata

Evidence has linked collagen loss with the onset of acute coronary events. OBJECTIVE: This study tested the hypothesis that selective MMP-13 collagenase inhibition increases collagen content in already established and nascent mouse atheromata. METHODS AND RESULTS: In vitro and in situ experiments do...

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Hlavní autoři: Quillard, Thibaut, Tesmenitsky, Yevgenia, Croce, Kevin, Travers, Richard, Shvartz, Eugenia, Koskinas, Konstantinos C., Sukhova, Galina, Aikawa, Elena, Aikawa, Masanori, Libby, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200308/
https://ncbi.nlm.nih.gov/pubmed/21903941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.231563
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