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Selective inhibition of matrix metalloproteinase 13 (MMP-13) increases collagen content of established mouse atheromata
Evidence has linked collagen loss with the onset of acute coronary events. OBJECTIVE: This study tested the hypothesis that selective MMP-13 collagenase inhibition increases collagen content in already established and nascent mouse atheromata. METHODS AND RESULTS: In vitro and in situ experiments do...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200308/ https://ncbi.nlm.nih.gov/pubmed/21903941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.231563 |
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