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TLR2 and neutrophils potentiate endothelial stress, apoptosis and detachment: implications for superficial erosion

AIMS: Superficial erosion of atheromata causes many acute coronary syndromes, but arises from unknown mechanisms. This study tested the hypothesis that Toll-like receptor-2 (TLR2) activation contributes to endothelial apoptosis and denudation and thus contributes to the pathogenesis of superficial e...

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Pubblicato in:Eur Heart J
Autori principali: Quillard, Thibaut, Araújo, Haniel Alves, Franck, Gregory, Shvartz, Eugenia, Sukhova, Galina, Libby, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458287/
https://ncbi.nlm.nih.gov/pubmed/25755115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv044
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