Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion

RATIONALE: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. Peptidyl arginine deiminase 4 (PAD4) participates i...

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Vydáno v:Circ Res
Hlavní autoři: Franck, Grégory, Mawson, Thomas L., Folco, Eduardo J., Molinaro, Roberto, Ruvkun, Victoria, Engelbertsen, Daniel, Liu, Xin, Tesmenitsky, Yevgenia, Shvartz, Eugenia, Sukhova, Galina K., Michel, Jean-Baptiste, Nicoletti, Antonino, Lichtman, Andrew, Wagner, Denisa, Croce, Kevin J., Libby, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014872/
https://ncbi.nlm.nih.gov/pubmed/29572206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312494
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