Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading

The ordered assembly of amyloidogenic proteins causes a wide spectrum of common neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. These diseases share common features with prion diseases, in which misfolded proteins can self-replicate and transmit disease across different h...

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Bibliographic Details
Published in:ACS Chem Neurosci
Main Authors: Kundel, Franziska, Hong, Liu, Falcon, Benjamin, McEwan, William A., Michaels, Thomas C. T., Meisl, Georg, Esteras, Noemi, Abramov, Andrey Y., Knowles, Tuomas J. P., Goedert, Michel, Klenerman, David
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014609/
https://ncbi.nlm.nih.gov/pubmed/29590529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00094
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