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Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme
Filamentous aggregates (fibrils) are regarded as the final stage in the assembly of amyloidogenic proteins and are formed in many neurodegenerative diseases. Accumulation of aggregates occurs as a result of an imbalance between their formation and removal. Here we use single-aggregate imaging to sho...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6381791/ https://ncbi.nlm.nih.gov/pubmed/30784595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.096 |
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