TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia

Large granular lymphocyte (LGL) leukemia results from clonal expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer (NK) cells. Chronic antigen stimulation is postulated to promote long-term survival of LGL leukemia cells through constitutive activation of multiple survival pathways, r...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Yang, Jun, LeBlanc, Francis R., Dighe, Shubha A., Hamele, Cait E., Olson, Thomas L., Feith, David J., Loughran, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014359/
https://ncbi.nlm.nih.gov/pubmed/29699990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-808816
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