Vitamin D decreases STAT phosphorylation and inflammatory cytokine output in T-LGL leukemia

Large granular lymphocyte leukemia (LGLL) is a rare incurable chronic disease typically characterized by clonal expansion of CD3+ cytotoxic T-cells. Two signal transducer and activator of transcription factors, STAT1 and STAT3, are constitutively active in T-LGLL. Disruption of this activation induc...

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Bibliographic Details
Published in:Cancer Biol Ther
Main Authors: Olson, Kristine C., Kulling, Paige M., Olson, Thomas L., Tan, Su-Fern, Rainbow, Rebecca J., Feith, David J., Loughran, Thomas P.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499847/
https://ncbi.nlm.nih.gov/pubmed/27715403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1235669
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