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Emergence of a STAT3 mutated NK clone in LGL leukemia
Large granular lymphocyte (LGL) leukemia is a chronic clonal lymphoproliferative disorder. Here, a T-LGL leukemia patient developed NK-LGL leukemia with residual leukemic T-LGL. TCRVβ usage and CDR3 sequence drifts were observed with disease progression. A STAT3 S614R mutation was identified in NK b...
Gardado en:
| Publicado en: | Leuk Res Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4327758/ https://ncbi.nlm.nih.gov/pubmed/25709890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2014.12.001 |
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