Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes

Calcitriol, the active form of vitamin D, has been well documented to act directly on immune cells and malignant cells. Activated T cells are one of the best characterized targets of calcitriol, with effects including decreasing inflammatory cytokine output and promoting anti-inflammatory cytokine p...

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Gepubliceerd in:Cytokine
Hoofdauteurs: Olson, Kristine C, Kulling, Paige M, Signorelli, Rossana, Hamele, Cait E, Olson, Thomas L, Conaway, Mark R., Feith, David J, Loughran, Thomas P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289695/
https://ncbi.nlm.nih.gov/pubmed/30455079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2018.09.016
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