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TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia

Large granular lymphocyte (LGL) leukemia results from clonal expansion of CD3(+) cytotoxic T lymphocytes or CD3(−) natural killer (NK) cells. Chronic antigen stimulation is postulated to promote long-term survival of LGL leukemia cells through constitutive activation of multiple survival pathways, r...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Yang, Jun, LeBlanc, Francis R., Dighe, Shubha A., Hamele, Cait E., Olson, Thomas L., Feith, David J., Loughran, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014359/
https://ncbi.nlm.nih.gov/pubmed/29699990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-808816
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