IMMU-21. TARGETING EGFR IN HYPOMUTATED PEDIATRIC BRAIN TUMORS USING THE D2C7 IMMUNOTOXIN

BACKGROUND: EGFR is a receptor tyrosine kinase that is hyperactivated or overexpressed in many human cancers. Compared with brain tumors in adults, pediatric tumors harbor few somatic mutations, which reduces the antigenic burden and number of potential molecular targets. Compared to checkpoint agen...

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Foilsithe in:Neuro Oncol
Main Authors: Landi, Daniel, Thompson, Eric, McLendon, Roger, Desjardins, Annick, Chandramohan, Vidya, Ashley, David, Bigner, Darell
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2018
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Abstracts
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012903/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.337
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