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IMMU-21. TARGETING EGFR IN HYPOMUTATED PEDIATRIC BRAIN TUMORS USING THE D2C7 IMMUNOTOXIN
BACKGROUND: EGFR is a receptor tyrosine kinase that is hyperactivated or overexpressed in many human cancers. Compared with brain tumors in adults, pediatric tumors harbor few somatic mutations, which reduces the antigenic burden and number of potential molecular targets. Compared to checkpoint agen...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012903/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.337 |
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