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Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma

Poliovirus oncolytic immunotherapy is a putatively novel approach to treat pediatric brain tumors. This work sought to determine expression of the poliovirus receptor (PVR), CD155, in low-grade and malignant pediatric brain tumors and its ability to infect, propagate, and inhibit cell proliferation....

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Thompson, Eric M, Brown, Michael, Dobrikova, Elena, Ramaswamy, Vijay, Taylor, Michael D, McLendon, Roger, Sanks, Jennifer, Chandramohan, Vidya, Bigner, Darell, Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044395/
https://ncbi.nlm.nih.gov/pubmed/29878245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly045
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