EXTH-51. GENETICALLY STABLE POLIOVIRUS VECTOR PLATFORM FOR DIPG IMMUNOTHERAPY

Options for the immunotherapy of diffuse intrinsic pontine glioma (DIPG), due to its anatomical location and inherent therapy resistance, are limited. The histone 3.3(K27M) mutation in ~80% of such tumors offers a unique opportunity for immunotherapy intervention, as it defines a high affinity, HLA-...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Gromeier, Matthias, Mosaheb, Mubeen, Dobrikova, Elena, Brown, Michael, Bigner, Darell, Ashley, David
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847841/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.382
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