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Cancer Immunotherapy with Recombinant Poliovirus Induces IFN-Dominant Activation of Dendritic Cells and Tumor Antigen-Specific CTLs

Tumors thrive in an immunosuppressive microenvironment that impedes antitumor innate and adaptive immune responses. Thus, approaches that can overcome immunosuppression and engage antitumor immunity are needed. This study defines the adjuvant and cancer immunotherapy potential of the recombinant pol...

詳細記述

保存先:
書誌詳細
出版年:Sci Transl Med
主要な著者: Brown, Michael C., Holl, Eda K., Boczkowski, David, Dobrikova, Elena, Mosaheb, Mubeen, Chandramohan, Vidya, Bigner, Darell D., Gromeier, Matthias, Nair, Smita K.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034685/
https://ncbi.nlm.nih.gov/pubmed/28931654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan4220
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