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Cancer Immunotherapy with Recombinant Poliovirus Induces IFN-Dominant Activation of Dendritic Cells and Tumor Antigen-Specific CTLs

Tumors thrive in an immunosuppressive microenvironment that impedes antitumor innate and adaptive immune responses. Thus, approaches that can overcome immunosuppression and engage antitumor immunity are needed. This study defines the adjuvant and cancer immunotherapy potential of the recombinant pol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Transl Med
मुख्य लेखकों: Brown, Michael C., Holl, Eda K., Boczkowski, David, Dobrikova, Elena, Mosaheb, Mubeen, Chandramohan, Vidya, Bigner, Darell D., Gromeier, Matthias, Nair, Smita K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034685/
https://ncbi.nlm.nih.gov/pubmed/28931654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan4220
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